A new French study has linked several common food preservatives used in store-bought foods to an increased risk of high blood pressure and cardiovascular diseases, raising fresh concerns about the health effects of additives commonly found in processed and ultra-processed foods.
The study, published in the European Heart Journal, found that people who consumed higher amounts of certain preservatives were more likely to develop hypertension, heart attacks and stroke over time.
Researchers analysed data from more than 112,000 participants enrolled in the NutriNet-Santé cohort, an ongoing French nutrition and health study that has tracked dietary habits since 2009.
Burden of heart disease in Nigeria
The findings come as Nigeria continues to face a growing burden of non-communicable diseases, particularly cardiovascular conditions such as hypertension, stroke and heart disease.
Hypertension, commonly known as high blood pressure, occurs when the force of blood pushing against the walls of blood vessels remains consistently too high. Over time, the condition can damage blood vessels and increase the risk of stroke, heart failure and kidney disease.
A stroke occurs when blood supply to part of the brain is blocked or when a blood vessel in the brain bursts, potentially causing paralysis, speech problems or death.
Heart attacks happen when blood flow to part of the heart becomes blocked, preventing oxygen from reaching heart muscles.
According to a report by PREMIUM TIMES, health experts and existing reports, hypertension remains one of the most common non-communicable diseases in Nigeria, with many cases undiagnosed until complications develop.
Preservatives linked to cardiovascular risk
According to the findings, preservatives used to prevent spoilage caused by bacteria, mould and yeast were associated with significantly higher cardiovascular risks.
The study reported that higher consumption of these preservatives was linked to a 29 per cent greater risk of elevated blood pressure and a 16 per cent increased risk of heart attacks and stroke.
Researchers identified three “non-antioxidant” preservatives strongly associated with hypertension. These include potassium sorbate, potassium metabisulphite and sodium nitrite.
Potassium sorbate is commonly used in baked goods, cheeses, sauces and wine, while potassium metabisulphite is often found in wine, juice, cider and beer.
Sodium nitrite is widely used in processed meats such as bacon, ham and deli meats.
The study also found that several antioxidant preservatives, often described as “natural”, were associated with increased cardiovascular risk.
These include ascorbic acid, sodium ascorbate, sodium erythorbate, citric acid and rosemary extracts, which are commonly used to prevent foods from turning brown or rancid.
Higher intake of these antioxidant preservatives was associated with a 22 per cent greater risk of high blood pressure.
Ascorbic acid, also known as vitamin C, was specifically linked to cardiovascular disease in the study.
Researchers noted that although ascorbic acid and citric acid naturally occur in fruits and vegetables, additives used in processed foods may not have the same health effects as naturally occurring compounds.
Ultra-processed foods under scrutiny
The findings add to growing evidence linking ultra-processed foods to poor health outcomes.
Researchers noted that preservatives are not limited to ultra-processed foods alone, as earlier findings showed that only about 35 per cent of preservative intake came from ultra-processed products.
Still, the study highlighted the widespread presence of preservatives across many commonly consumed foods and reinforced recommendations encouraging people to consume more fresh and minimally processed foods.
Researchers advised consumers to prioritise fresh, uncooked and minimally processed foods where possible.
Frozen foods preserved through low temperatures rather than additives were also identified as preferable alternatives.
Long-term dietary tracking
To conduct the research, participants recorded all foods and drinks consumed over three days every six months, including brand names.
Researchers then matched these records with ingredient databases to estimate preservative exposure over several years.
Medical records from the French national healthcare system were used to track diagnoses of hypertension and cardiovascular disease over the study period.
The researchers examined 58 preservatives in total and conducted detailed analysis on 17 additives consumed by at least 10 per cent of participants. Eight of those preservatives were associated with increased hypertension risk over the following decade.
The study builds on previous research linking similar preservatives to increased risks of cancer and type 2 diabetes.
Earlier findings identified preservatives such as sodium nitrite, potassium nitrate, sorbates, potassium metabisulphite, acetates and acetic acid as being associated with higher risks of prostate cancer, breast cancer and other cancers.
Several of the same preservatives were also previously linked to a significantly increased risk of developing type 2 diabetes.
Although the researchers noted that the findings do not establish direct cause and effect, they said the results highlight the need for further investigation into the long-term health effects of food additives and preservatives.
Menopause, the natural stage marking the end of a woman’s reproductive years, can significantly affect bone health and increase the risk of osteoporosis and fractures due to declining oestrogen levels, a medical expert has said.
Although menopause has important health implications, it remains a frequently overlooked issue within Nigeria’s sexual and reproductive health and rights framework.
According to the World Health Organisation (WHO), menopause occurs when a woman’s menstrual periods stop permanently because of declining levels of oestrogen and the loss of ovarian follicular function. As a result, the ovaries stop releasing eggs for fertilisation, making natural conception no longer possible.
Common symptoms associated with menopause include hot flushes, night sweats, irregular menstrual flow, vaginal dryness, pain during sexual intercourse, urinary incontinence, sleep disturbances, mood changes, anxiety and depression.
Perimenopause refers to the transition period leading to menopause and extends until one year after the final menstrual period, while postmenopause begins after a woman has gone 12 consecutive months without menstruation.
In Nigeria, women generally attain menopause around the age of 48 and above as part of the natural ageing process.
Menopause and bone health
Speaking with PT Health Watch, Qudus Lawal, an obstetrician and gynaecologist, said menopause disrupts hormonal balance, leading to increased bone breakdown and reduced bone formation.
According to him, while nearly all women experience some degree of bone loss after menopause because of declining oestrogen levels, not all will develop osteoporosis or sustain fractures.
He explained that bone density before menopause plays a major role in determining a woman’s risk of osteoporosis later in life.
Using a financial analogy, Mr Lawal described bone health as a balance between deposits and withdrawals.
“The stronger the bone density a woman builds before menopause, the better protected she is against the accelerated loss that occurs afterwards,” he said.
Why bone loss increases after menopause
Mr Lawal explained that oestrogen normally suppresses osteoclasts, the cells responsible for breaking down bone tissue.
However, when oestrogen levels fall after menopause, these cells become more active, while osteoblasts, the cells responsible for building new bone, are unable to replace bone at the same rate.
This imbalance gradually weakens bones and increases the risk of osteoporosis and fractures.
Maintaining healthy bones after menopause
Mr Lawal recommended a combination of proper nutrition, regular exercise and preventive healthcare measures to maintain bone health after menopause.
He advised women to consume balanced diets rich in calcium and vitamin D, engage in weight-bearing and muscle-strengthening exercises, and take steps to prevent falls.
“When you take foods and supplements that are rich in those essential nutrients, it helps build the bone,” he said.
He stressed the importance of early intervention, noting that bone density loss is often silent and may not produce symptoms until complications occur.
“One of the ways people present is that they grow shorter. Normally, once you get to a certain age after puberty, you are not supposed to grow shorter.
“But many of our mothers begin to lose height over time, which may result from age-related spinal degeneration and bone loss,” he said.
According to him, many women only become aware of significant bone loss after suffering fractures.
“The fracture can be due to a fall, sometimes a little push that you normally have without having symptoms. Just a little trip in the bathroom could lead to a major fracture,” he added.
Mr Lawal noted that in some countries, bone density screening forms part of routine wellness checks for postmenopausal women, helping identify individuals at high risk and allowing for early intervention.
He urged women to adopt healthy lifestyles and prioritise bone health long before menopause.
According to him, the goal is to ensure women build and maintain strong bone density before menopause to minimise the impact of hormonal changes later in life.
Nigeria is intensifying efforts to expand access to Multiple Micronutrient Supplements (MMS) for pregnant women, with health authorities pushing for increased local production and sustainable financing to reduce dependence on donor support.
The move was highlighted on Thursday in Abuja during a validation meeting on findings from the 2025 Market Landscaping and Segmentation Analysis.
Speaking at the event, Olufunmilola Adegbite, Director and Head of the Nutrition Department at the Federal Ministry of Health and Social Welfare, said strengthening domestic manufacturing would be crucial to achieving the country’s maternal health targets.
Director and Head of the Nutrition Department at the Federal Ministry of Health and Social Welfare, Olufunmilola Adegbite
“Local production will be critical in achieving the country’s ambition for reaching pregnant women with MMS and ensuring long-term sustainability,” she said.
According to Ms Adegbite, local manufacturing would improve the availability of supplements, reduce dependence on imports, and protect supply chains from global disruptions.
Six-state study
The 2025 market landscape analysis covered Lagos, Kano, Bauchi, Imo, Niger and Bayelsa, selected to reflect Nigeria’s diverse geographical zones and market segments.
Commissioned by the Federal Ministry of Health and Social Welfare in collaboration with Sight and Life and the development Research and Projects Centre (dRPC), the study examined financing systems and broader implementation requirements needed to support nationwide MMS scale-up.
Researchers assessed existing health financing mechanisms alongside key implementation enablers, including supply chains, regulatory frameworks and stakeholder engagement.
Why MMS matters
MMS are daily antenatal supplements containing iron, folic acid and other essential vitamins and minerals needed to support maternal nutrition and healthier birth outcomes.
Unlike conventional iron-folic acid supplements, MMS provide a broader range of micronutrients.
Evidence suggests the intervention can further reduce the risks of low birth weight, preterm delivery and other adverse pregnancy outcomes.
Ms Adegbite said Nigeria has made significant progress in aligning with global maternal nutrition standards.
According to her, MMS was approved for use in 2021, incorporated into the National Essential Medicines List and integrated into national guidelines on micronutrient deficiency control and antenatal care management.
“These achievements demonstrate Nigeria’s commitment to improving maternal and newborn nutritional outcomes,” she said.
Financing remains critical
Despite these policy gains, Ms Adegbite said considerable work remains to ensure effective implementation and wider access.
She identified sustainable financing as a major requirement for expansion, noting that mechanisms such as the National Health Insurance Authority (NHIA), the Basic Healthcare Provision Fund (BHCPF) and dedicated federal and state budget allocations could help support broader coverage.
She added that findings from the market analysis would provide evidence to guide policy decisions, investment priorities and implementation strategies.
Although progress has been made in institutionalising MMS, she said challenges persist in supply systems, regulation, financing and stakeholder coordination.
Concerns over donor dependence
In her remarks, the Country Manager of Sight and Life, Zainab Abubakar, said the study sought to identify sustainable pathways for financing MMS within Nigeria’s health system.
Ms Abubakar noted that inadequate funding, limited insurance coverage and heavy reliance on out-of-pocket spending continue to restrict access to maternal nutrition services.
“The research assessed the health financing landscape in Nigeria to identify viable pathways for sustainable domestic financing,” she said.
“It explored opportunities for resource mobilisation, evaluated potential funding mechanisms, highlighted implementation bottlenecks and developed context-specific recommendations.”
‘Women’s issues need funding’
Also speaking, the Special Adviser to the President on Health and dRPC board member, Salma Anas, called for stronger political commitment to maternal nutrition programmes.
Ms Anas said anaemia in pregnancy remains a major public health challenge and urged leaders to prioritise investments that benefit women and children.
According to her, programmes targeting women and children often struggle to attract adequate funding because they are incorrectly viewed as issues affecting only women.
“Every woman’s issue is a man’s business,” she said.
“Let us do away with the woman’s issue. Let’s budget it. Let’s release it and let it be used for the intended purpose.”
Background
Nigeria adopted MMS following global recommendations and growing evidence that the intervention provides greater nutritional benefits than traditional iron-folic acid supplements.
According to UNICEF, MMS contains 15 essential vitamins and minerals and has become the global reference standard for maternal micronutrient supplementation.
PREMIUM TIMES reported in 2024 that the federal government distributed about 1.3 million bottles of MMS to pregnant women across 12 states during the early phase of implementation.
UNICEF later announced that Nigeria would receive an additional 3 million bottles in 2025 through the Child Nutrition Fund, following the delivery of 3 million bottles in 2024.
However, with an estimated 12 million pregnancies recorded annually, stakeholders say existing supplies remain insufficient, highlighting the need for expanded coverage and stronger domestic investment.
They argue that shifting from donor-dependent supply chains to local manufacturing and market-based financing mechanisms will be essential to ensuring the long-term sustainability of MMS scale-up.