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In Harvard study, AI offered more accurate diagnoses than emergency room doctors

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A new study examines how large language models perform in a variety of medical contexts, including real emergency room cases — where at least one model seemed to be more accurate than human doctors.

The study was published this week in Science and comes from a research team led by physicians and computer scientists at Harvard Medical School and Beth Israel Deaconess Medical Center. The researchers said they conducted a variety of experiments to measure how OpenAI’s models compared to human physicians.

In one experiment, researchers focused on 76 patients who came into the Beth Israel emergency room, comparing the diagnoses offered by two attending physicians to those generated by OpenAI’s o1 and 4o models. These diagnoses were assessed by two other attending physicians, who did not know which ones came from humans and which came from AI.

“At each diagnostic touchpoint, o1 either performed nominally better than or on par with the two attending physicians and 4o,” the study said, adding that the differences “were especially pronounced at the first diagnostic touchpoint (initial ER triage), where there is the least information available about the patient and the most urgency to make the correct decision.”

In Harvard Medical School’s press release about the study, the researchers emphasized that they did not “pre-process the data at all” — the AI models were presented with the same information that was available in the electronic medical records at the time of each diagnosis.

With that information, the o1 model managed to offer “the exact or very close diagnosis” in 67% of triage cases, compared to one physician who had the exact or close diagnosis 55% of the time, and to the other who hit the mark 50% of the time.

“We tested the AI model against virtually every benchmark, and it eclipsed both prior models and our physician baselines,” said Arjun Manrai, who heads an AI lab at Harvard Medical School and is one of the study’s lead authors, in the press release.

To be clear, the study didn’t claim that AI is ready to make real life-or-death decisions in the emergency room. Instead, it said the findings show an “urgent need for prospective trials to evaluate these technologies in real-world patient care settings.”

The researchers also noted that they only studied how models performed when provided with text-based information, and that “existing studies suggest that current foundation models are more limited in reasoning over nontext inputs.”

Adam Rodman, a Beth Israel doctor who’s also one of the study’s lead authors, warned the Guardian that there’s “no formal framework right now for accountability” around AI diagnoses, and that patients still “want humans to guide them through life or death decisions [and] to guide them through challenging treatment decisions”.

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Health

Study links common food preservatives to higher risk of hypertension, heart disease

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A new French study has linked several common food preservatives used in store-bought foods to an increased risk of high blood pressure and cardiovascular diseases, raising fresh concerns about the health effects of additives commonly found in processed and ultra-processed foods.

The study, published in the European Heart Journal, found that people who consumed higher amounts of certain preservatives were more likely to develop hypertension, heart attacks and stroke over time.

Researchers analysed data from more than 112,000 participants enrolled in the NutriNet-Santé cohort, an ongoing French nutrition and health study that has tracked dietary habits since 2009.

Burden of heart disease in Nigeria

The findings come as Nigeria continues to face a growing burden of non-communicable diseases, particularly cardiovascular conditions such as hypertension, stroke and heart disease.

Hypertension, commonly known as high blood pressure, occurs when the force of blood pushing against the walls of blood vessels remains consistently too high. Over time, the condition can damage blood vessels and increase the risk of stroke, heart failure and kidney disease.

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A stroke occurs when blood supply to part of the brain is blocked or when a blood vessel in the brain bursts, potentially causing paralysis, speech problems or death.

Heart attacks happen when blood flow to part of the heart becomes blocked, preventing oxygen from reaching heart muscles.

According to a report by PREMIUM TIMES, health experts and existing reports, hypertension remains one of the most common non-communicable diseases in Nigeria, with many cases undiagnosed until complications develop.

Preservatives linked to cardiovascular risk

According to the findings, preservatives used to prevent spoilage caused by bacteria, mould and yeast were associated with significantly higher cardiovascular risks.

The study reported that higher consumption of these preservatives was linked to a 29 per cent greater risk of elevated blood pressure and a 16 per cent increased risk of heart attacks and stroke.

Researchers identified three “non-antioxidant” preservatives strongly associated with hypertension. These include potassium sorbate, potassium metabisulphite and sodium nitrite.

Potassium sorbate is commonly used in baked goods, cheeses, sauces and wine, while potassium metabisulphite is often found in wine, juice, cider and beer.

Sodium nitrite is widely used in processed meats such as bacon, ham and deli meats.

The study also found that several antioxidant preservatives, often described as “natural”, were associated with increased cardiovascular risk.

These include ascorbic acid, sodium ascorbate, sodium erythorbate, citric acid and rosemary extracts, which are commonly used to prevent foods from turning brown or rancid.

Higher intake of these antioxidant preservatives was associated with a 22 per cent greater risk of high blood pressure.

Ascorbic acid, also known as vitamin C, was specifically linked to cardiovascular disease in the study.

Researchers noted that although ascorbic acid and citric acid naturally occur in fruits and vegetables, additives used in processed foods may not have the same health effects as naturally occurring compounds.

Ultra-processed foods under scrutiny

The findings add to growing evidence linking ultra-processed foods to poor health outcomes.

Researchers noted that preservatives are not limited to ultra-processed foods alone, as earlier findings showed that only about 35 per cent of preservative intake came from ultra-processed products.

Still, the study highlighted the widespread presence of preservatives across many commonly consumed foods and reinforced recommendations encouraging people to consume more fresh and minimally processed foods.

Researchers advised consumers to prioritise fresh, uncooked and minimally processed foods where possible.

Frozen foods preserved through low temperatures rather than additives were also identified as preferable alternatives.

Long-term dietary tracking

To conduct the research, participants recorded all foods and drinks consumed over three days every six months, including brand names.

Researchers then matched these records with ingredient databases to estimate preservative exposure over several years.

Medical records from the French national healthcare system were used to track diagnoses of hypertension and cardiovascular disease over the study period.

The researchers examined 58 preservatives in total and conducted detailed analysis on 17 additives consumed by at least 10 per cent of participants. Eight of those preservatives were associated with increased hypertension risk over the following decade.

READ ALSO: WHO, EU launch health support project as Nigeria battles multiple disease outbreaks

Links to cancer, diabetes

The study builds on previous research linking similar preservatives to increased risks of cancer and type 2 diabetes.

Earlier findings identified preservatives such as sodium nitrite, potassium nitrate, sorbates, potassium metabisulphite, acetates and acetic acid as being associated with higher risks of prostate cancer, breast cancer and other cancers.

Several of the same preservatives were also previously linked to a significantly increased risk of developing type 2 diabetes.

Although the researchers noted that the findings do not establish direct cause and effect, they said the results highlight the need for further investigation into the long-term health effects of food additives and preservatives.

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NPFL: Rangers International Crowned Champions as Remo Stars’ Fate Hangs in the Balance

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Rangers International emerged champions of the 2025/2026 Nigeria Premier Football League season after a dramatic 2-1 away victory over Ikorodu City on the final day of the campaign.

Midfielder Chidiebere Nwobodo proved to be the hero for the Flying Antelopes, scoring twice in the 30th and 52nd minutes before Moses Ali pulled one back for Ikorodu City in the 58th minute. The crucial victory saw Rangers finish top of the table with 68 points, sealing their second NPFL title in three seasons.

Read Also: Jide Oguntuase Backs Ex-International Tournament as Platform for Grassroots Development

Title rivals Rivers United kept up the pressure with an emphatic 3-0 win over Katsina United in Port Harcourt. Chijioke Mbaoma netted a brace while Aniekeme Okon also got on the scoresheet, but the result was not enough as Rivers United finished one point behind the champions on 67 points.

At the bottom of the table, Remo Stars’ fate remains uncertain following a 1-1 draw against Bendel Insurance in Benin City. Victor Mbaoma had given the Sky Blue Stars the lead in the first half, but Chijioke Akuneto struck deep into stoppage time to deny them a crucial victory.

However, Remo Stars’ survival will now depend on the outcome of the postponed Kun Khalifat match, which was disrupted by heavy rainfall and will be concluded on Monday morning. A victory for Kun Khalifat would confirm Remo Stars’ relegation to the Nigeria National League.

Elsewhere, Shooting Stars lost 1-0 to Niger Tornadoes but still secured a CAF Confederation Cup ticket after finishing third on the table.

Other final-day results saw Enyimba thrash El-Kanemi Warriors 3-0, while Bayelsa United hammered Kwara United 4-0.

In Akure, Warri Wolves boosted their survival hopes with a 2-1 victory over Abia Warriors, while Plateau United edged Kano Pillars 1-0 thanks to a dramatic stoppage-time strike from Victor Dawa.

Bayelsa United and Wikki Tourists have already been confirmed relegated to the Nigeria National League.

Results At A Glance

Niger Tornadoes 1-0 Shooting Stars
Enyimba 3-0 El-Kanemi Warriors
Bayelsa United 4-0 Kwara United
Bendel Insurance 1-1 Remo Stars
Ikorodu City 1-2 Rangers International
Rivers United 3-0 Katsina United

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