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9.5m children received no routine vaccine in 57 countries in 2025

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Gavi, the Vaccine Alliance, says 9.5 million children in 57 supported countries received no routine vaccine in 2025, despite gains in global immunisation.

The figure, described as the number of “zero-dose” children, was contained in Gavi’s 2025 Annual Progress Report, which reviewed the alliance’s 2021-2025 strategic period.

Gavi defines zero-dose children as infants who have not received the first dose of a diphtheria, tetanus and pertussis-containing vaccine by the end of their first year.

Number falls from 2021 peak

According to the report, the number of zero-dose children in 2025 was 600,000 lower than in 2024 and 25 per cent lower than the peak recorded in 2021 following disruptions to routine immunisation caused by the COVID-19 pandemic.

However, the figure remained four per cent above the 2019 baseline, partly because of continued growth in the number of children being born.

Gavi said children living in fragile, conflict-affected and humanitarian settings remain among those most likely to be missed by immunisation programmes.

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Nigeria remains one of the countries with the highest number of zero-dose children. UNICEF estimated that about 2.2 million Nigerian children had never received a routine vaccine in 2025, the highest number in Africa.

Nigeria records gains in targeted areas

The report highlighted Nigeria, Ethiopia and Pakistan among countries where emerging data showed stronger immunisation coverage gains in sub-national areas that received greater Gavi focus and investment during the 2021-2025 period.

Gavi said the findings underscored the value of targeted, equity-focused investments in reaching communities that are being missed by routine immunisation.

The report also identified Nigeria among countries covered by Gavi’s Zero-Dose Learning Hubs, which examined what works and what does not in identifying and reaching zero-dose and under-immunised children.

The findings from Nigeria, Bangladesh, Mali and Uganda highlighted several issues, including gender-related barriers to immunisation.

73m children immunised in 2025

Despite the number of zero-dose children, Gavi said more than 73 million children were immunised through routine programmes with its support in 2025.

More than 351 million children were immunised during the 2021-2025 strategic period, “exceeding Gavi’s target of 300 million children.”

“By end 2025, Gavi-supported countries had immunised more than 1.3 billion unique children with Gavi support since 2000, exceeding our Investment Opportunity 2021-2025 commitment of more than 1.1 billion children immunised by 2025,” it noted.

Gavi said vaccination averted more than 2.2 million future deaths in 2025, bringing the total number of future deaths averted through its supported vaccination programmes to more than 7.8 million during the 2021-2025 period.

Generated economic benefits

The report said immunisation programmes generated more than $30 billion in economic benefits for Gavi-supported countries in 2025, the highest amount recorded in a single year.

The benefits were calculated from the costs of illness averted, including medical and associated costs, caretaker wages and productivity losses resulting from disability or death.

Gavi said the programmes generated more than $104 billion in economic benefits between 2021 and 2025 and more than $308 billion between 2000 and 2025.

Countries also contributed a record $301 million towards the co-financing of Gavi-supported vaccines in 2025, an 18 per cent increase from 2024.

About 80 per cent of the contribution came from domestic resources, while “approximately 20 per cent from low-interest loans from the World Bank.”

Gavi said countries had contributed a total of $2.2 billion towards vaccine co-financing since the policy was introduced in 2008.

More children

For its 2026 to 2030 strategic period, Gavi said it aims to protect another 500 million children through immunisation and avert between eight million and nine million future deaths.

READ ALSO:New TB vaccines could save 7.3m lives by 2050 – Gavi 

The Alliance also targets more than $100 billion in economic benefits during the period. Gavi said it would place greater emphasis on reaching zero-dose and under-immunised children while strengthening the sustainability of national immunisation programmes.

In her comments, Gavi Chief Executive Officer, Sania Nishtar, said the results showed that immunisation generates benefits beyond preventing disease. “However, when it comes to immunisation we know that the return on investment extends far beyond health to supporting sustainable, inclusive economic growth,” Ms Nishtar said.

WHO Director-General, Tedros Ghebreyesus, also said immunisation delivers massive gains in lives saved and diseases prevented, but also in terms of economic benefits.

“Countries understand that the cost of failing to vaccinate is far too great, while the benefits extend across families, communities, economies and future generations,” Mr Ghebreyesus was quoted to have said.


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Health

Ebola: Africa CDC warns continent ‘not winning’ as cases surpass 10,000

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The Director-General of the Africa Centres for Disease Control and Prevention (Africa CDC), Jean Kaseya, has warned that Africa is not yet winning the fight against the ongoing Ebola outbreak, as confirmed cases have surpassed 10,000 and deaths approach 5,000.

Mr Kaseya made the remarks on Wednesday at an extraordinary meeting of African health ministers convened to discuss the outbreak and strengthen a coordinated continental response.

“I have worked on Ebola outbreaks for more than 30 years. I have never stopped feeling the weight of each life lost,” Mr Kaseya said.

“Yesterday I stood before more than 40 African Ministers and said what the data tells us: we are not winning so far. 10,172 confirmed cases. 4,932 people are gone.”

He said the ministers agreed to prepare every country for possible Ebola cases, coordinate responses across borders and keep borders open while strengthening surveillance.

“Ebola anywhere in Africa demands preparedness everywhere in Africa. We will get there, together,” he said.

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Ebola outbreak

The current outbreak is caused by the Bundibugyo virus, a species of Ebola virus, and was first declared in the Democratic Republic of the Congo (DRC) in May 2026.

According to the latest figures from the World Health Organisation (WHO), the outbreak has recorded 10,172 confirmed cases and 4,932 deaths across five countries: DRC, Uganda, France, Kenya and Nigeria.

The DRC accounts for the majority of the cases, with 10,141 confirmed cases and 4,928 deaths as of 26 October. It has affected eight provinces.

Kenya has recorded nine confirmed cases and two deaths, while Uganda has recorded 20 confirmed cases and two deaths, alongside one probable case and one probable death.

France and Nigeria recorded one imported case each, with no deaths.

The first Nigerian case was confirmed on 20 October after a traveller with a history of travel to Uganda tested positive for the virus. The patient was subsequently medically evacuated to Switzerland, while contacts continue to be monitored.

According to the Nigeria Centre for Disease Control and Prevention (NCDC), 54 contacts linked to the Nigerian case had been traced and were under follow-up as of 26 October.

Africa’s response

Mr Kaseya said the scale of the outbreak requires countries across the continent to strengthen preparedness even where no active cases have been detected.

He said the meeting brought together more than 40 African health ministers and that countries agreed to work together on surveillance, preparedness and cross-border coordination.

He also highlighted the economic and social consequences of the 2014-2016 West Africa Ebola outbreak, saying about five million children were kept out of school, about 23,000 children lost their parents and nearly $3 billion in gross domestic product was lost.

“We already know what an uncontrolled Ebola outbreak costs,” he said. “The data is hard to hear, but it is also our best chance to change course.”

READ ALSO: Ebola: Survivors can transmit virus through sex, but not sweat or saliva – WHO

WHO has advised against restrictions on travel to or trade with affected countries, while emphasising continued surveillance and preparedness because of the risk of cross-border transmission.

Nigeria’s case has also raised questions about how the virus is moving across the region. Genomic sequencing showed that the virus detected in Nigeria is closely related to the strain identified in Kenya, with the two samples differing by a single mutation, according to the Coordinating Minister of Health and Social Welfare, Muhammad Pate.

However, Mr Pate said the finding does not establish a direct epidemiological link between Nigeria’s case and Kenya’s first confirmed case. Further investigation is needed to determine how the virus reached Nigeria.


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Health

Nigeria’s health insurance enrolment rises to 23 million — NHIA

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Nigeria’s health insurance enrolment increased to 23.06 million people in the second quarter of 2026, up from 16.2 million in late 2023, the Director-General of the National Health Insurance Authority (NHIA), Kelechi Ohiri, has said.

Mr Ohiri disclosed this on Thursday while delivering the keynote address at the 11th Future of Health Conference organised by Nigeria Health Watch in Abuja.

He said enrolment across federal, state and private health insurance schemes grew by 42.35 per cent over the period.

However, Mr Ohiri said increasing enrolment alone would not guarantee access to healthcare or protect Nigerians from financial hardship.

“We constantly face the reality of a difference between an insurance coverage record and genuine financial risk protection,” he said.

“An insurance card in a citizen’s pocket is meaningless if it does not grant immediate access to a functional facility, guarantee essential medicines, protect against catastrophic out-of-pocket expenses, and deliver dignity during medical emergencies.”

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Improving access and accountability

Mr Ohiri said the NHIA had introduced measures to help enrollees understand their benefits, access support and hold healthcare providers accountable.

These include the MyNHIA mobile application and an online self-enrolment portal. He said the authority also distributed enrollee charters and benefit package details through interactive QR codes at accredited health facilities nationwide.

According to him, the codes enable enrollees to check the consultations, diagnostic services and medicines covered by their insurance packages.

Mr Ohiri said the NHIA also strengthened its complaints management system to address grievances involving enrollees, healthcare facilities and health maintenance organisations (HMOs).

Mr Ohiri said the NHIA received and tracked 2,209 complaints through social media, telephone calls, walk-in desks, call centres and letters.

He said 82 per cent of the complaints were resolved within 48 hours, adding that the authority secured direct refunds for enrollees who had been improperly charged by healthcare facilities.

The NHIA also issued formal warnings to facilities and delisted providers for persistent non-compliance, he said.

“That is how regulation converts coverage into genuine financial protection,” Mr Ohiri said.

Targeting vulnerable populations

The NHIA boss said the authority was expanding insurance access for vulnerable Nigerians through targeted programmes supported by public subsidies, grants and public-private partnerships.

He said under the Basic Health Care Provision Fund (BHCPF) Gateway, enrolment increased from 2.6 million people in the second quarter of 2026 to 3.2 million in the third quarter, representing a 20.5 per cent increase.

He added that all the enrollees under the gateway had been biometrically verified using their National Identification Numbers (NINs).

Mr Ohiri also highlighted a programme established in partnership with the Global Fund to provide health insurance coverage for key population groups living with or affected by major infectious diseases in Gombe, Anambra, Ebonyi and Kwara states.

He said enrolment under the programme increased from 25,815 beneficiaries in the fourth quarter of 2025 to 58,447 in the third quarter of 2026.

He said women accounted for 68 per cent of the enrollees, while all beneficiaries had been biometrically verified using their NINs.

Future of Health is Now

The conference, themed “From Innovation to Impact: The Future of Health is Now”, brought together stakeholders to discuss how innovations, investments, research and policies can translate into measurable improvements in healthcare delivery.

Mr Ohiri said health innovations must solve practical problems, generate evidence, remain financially sustainable and become integrated into existing systems to achieve impact at scale.

He said the NHIA’s reforms were intended to build a health financing system that protects Nigerians from financial hardship while improving access to healthcare.

“The future of health is not a distant vision,” he said.

“Through strategic purchasing, rigorous evidence, and commitment to equity, the future of health is happening right now.”

READ ALSO: Experts call for wider adoption of proven health innovations in Nigeria

In her remarks, the Managing Director of Nigeria Health Watch, Vivianne Ihekweazu, said Nigeria must look beyond the development of health innovations to the financing, policies, procurement processes and data systems needed to sustain them and expand their reach.

Mrs Ihekweazu said the 11th edition of the conference provided an opportunity to reflect on lessons from more than a decade of discussions on universal health coverage, healthcare financing, technology and the role of the private sector in strengthening Nigeria’s health system.

She said innovations would only deliver meaningful health outcomes if policymakers prioritised scale and sustainability from the outset.

Citing a review of digital innovations in maternal and newborn health in Nigeria, she said none of the 10 interventions examined had achieved sustained scale, largely because they lacked clear ownership within the health system and a pathway into routine service delivery.


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