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Africa CDC blames global neglect for lack of Bundibugyo Ebola vaccine

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The Africa Centres for Disease Control and Prevention (Africa CDC) has criticised the lack of investment in developing a vaccine against the Bundibugyo strain of Ebola, nearly two decades after the virus was first identified in Uganda.

The agency’s Director-General, Jean Kaseya, said the absence of an approved vaccine reflected the international community’s failure to prioritise diseases largely affecting African countries.

Speaking on Channels Television’s The Morning Brief on Thursday, Mr Kaseya argued that the situation would have been different if outbreaks of the disease had occurred in Western countries.

“If this outbreak was in Western countries, vaccines will already be available,” he said.

Mr Kaseya said the Bundibugyo virus was first identified 19 years ago and had caused three outbreaks, yet no vaccine had been approved specifically to prevent the disease.

He said the situation highlighted the need for African countries to invest in vaccine research, clinical trials and local manufacturing rather than depend almost entirely on international partners.

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Africa pushes for vaccine development

Mr Kaseya said Africa CDC was working with partners to advance research into vaccines against the Bundibugyo virus, including efforts involving an African manufacturer in Egypt.

He said the agency was also collaborating with the Democratic Republic of the Congo (DRC) and Uganda to explore possible research and emergency-use options involving existing Ebola vaccines.

One of the vaccines under consideration, Ervebo, is approved for preventing disease caused by the Ebola virus, formerly known as the Zaire strain. However, it is not approved for preventing disease caused by the Bundibugyo virus.

Mr Kaseya said the ongoing efforts were intended to strengthen Africa’s ability to respond to disease outbreaks without relying heavily on external support for vaccines and other essential medical products.

“We don’t want to see Africa left behind,” he said.

He maintained that Africa had the scientific expertise, skilled personnel and manufacturing potential needed to develop and produce vaccines, medicines and diagnostic tools.

Nigeria’s Ebola case

Mr Kaseya’s remarks come as Nigeria responds to its first confirmed case of Ebola virus disease, following an outbreak that began in the DRC in May.

As PREMIUM TIMES reported on Thursday, the confirmed patient is the wife of a diplomat who had travelled to Kampala, Uganda, before returning to Abuja. She developed symptoms shortly after her return and initially sought treatment for what was believed to be malaria before her infection was confirmed.

The Nigerian government said the patient is receiving medical care in isolation, while health authorities have identified 44 contacts for monitoring.

The case makes Nigeria the latest country affected by the cross-border spread of the disease.

The ongoing outbreak has also affected the DRC and Kenya, while Uganda previously recorded cases before declaring its outbreak over.

Greater control of vaccine production

Mr Kaseya said the response to the current outbreak should mark a turning point in how Africa prepares for and manages infectious disease emergencies.

He identified three priorities: expanding vaccine manufacturing on the continent, improving coordination among international partners and increasing domestic funding for public health responses.

According to him, 28 African countries had contributed funding to support the response, which he described as a significant demonstration of growing continental ownership of health emergencies.

He said African countries must continue to mobilise resources rather than depend almost entirely on international assistance when outbreaks occur.

Mr Kaseya also stressed that the organisation had a responsibility to protect the continent’s estimated 1.5 billion people across 55 countries, adding that its response to the Nigerian case was being coordinated with the country’s health authorities and international partners.

He said that the current outbreak should accelerate efforts to build a more self-reliant African health system, with stronger domestic financing and greater capacity to develop and produce essential medical supplies.

“After Ebola, Bundibugyo will not be like before Bundibugyo,” he said, expressing confidence that the continent’s approach to vaccine development and outbreak response would change.


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Ebola: Africa CDC assures patient confidentiality amid contact tracing

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The Africa Centres for Disease Control and Prevention (Africa CDC) has assured the public that patients’ personal information will remain confidential during ongoing Ebola containment operations, as authorities work to trace people who may have been exposed to the disease.

Wessam Mankoula, an epidemiologist and the agency’s Director of Emergency Preparedness and Response, gave the assurance during a virtual press briefing on Thursday. He explained that patients’ information was shared only with authorised investigators conducting contact tracing.

He said the information would not be disclosed publicly, emphasising the importance of protecting patients’ privacy during outbreak investigations.

The assurance follows the Nigerian government’s confirmation on Tuesday of an Ebola case in the Federal Capital Territory (FCT).

The patient, a woman who recently arrived in Nigeria on an international flight from Uganda, is receiving medical care in isolation at a private hospital in the FCT.

Contact tracing

Mr Mankoula said Nigeria’s National Reference Laboratory confirmed that the imported case involved the Bundibugyo strain of the Ebola virus.

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He said 44 high-risk contacts had been identified, and the government was working to identify others who might have been exposed.

Contact tracing involves identifying and monitoring people who may have been in contact with an infected person, so possible infections can be detected early and further transmission limited.

Mr Mankoula also said investigators were examining a possible link between the Nigerian case and a case in Kenya. Both individuals had travelled through Entebbe International Airport in Uganda on 3 October.

He stressed that a connection remained under investigation and had not been established.

READ ALSO: Ebola: FG orders strict screening at Nigeria’s entry points

Regional response

Mr Mankoula said Africa CDC was working with partners, including the WHO, to strengthen disease surveillance and support preparedness measures. These included providing testing supplies at border areas near the Democratic Republic of the Congo (DRC).

Nigeria’s case comes amid an Ebola outbreak in the DRC involving the Bundibugyo virus.

According to figures attributed to the European Centre for Disease Prevention and Control (ECDC), the DRC had recorded 9,552 confirmed cases and 4,602 related deaths as of 19 October, based on data up to 18 October.

The outbreak has affected 66 of the country’s 178 health zones across eight provinces, with Ituri the most affected province.

These developments have heightened concerns about Ebola’s cross-border spread and the need for countries to strengthen surveillance, laboratory testing and coordination to identify suspected cases promptly.

Africa CDC continues to work with national health authorities and international partners to support outbreak response efforts and limit further transmission.


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Ebola: Swiss government says Nigeria’s patient likely contracted virus in Uganda

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Nigeria’s first confirmed Ebola patient in more than a decade is believed to have contracted the virus while travelling in Uganda, although health authorities are yet to establish the source of her infection.

According to a report by Reuters, the Swiss Federal Department of Foreign Affairs told the newspaper in an emailed statement on Thursday that the patient, a Ugandan-born woman married to a Swiss diplomat based in Abuja, has been receiving treatment at a private clinic in the Nigerian capital for about a week.

According to Reuters, the statement said the woman was believed to have contracted the virus during a visit to Uganda about two weeks earlier. Her husband, who travelled with her, is in isolation but has not developed symptoms.

However, the World Health Organisation (WHO) and the Africa Centres for Disease Control and Prevention (Africa CDC) said they had not received verified information that the woman travelled to the Democratic Republic of the Congo (DRC), where the current Ebola outbreak began.

Conflicting travel accounts

According to Reuters, Ugandan authorities had earlier said the woman travelled to eastern DRC before transiting through Uganda.

However, Africa CDC official Wessam Mankoula said on Thursday that there was no validated information confirming that the patient had travelled to the DRC.

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Mr Mankoula said Nigeria and Uganda were exchanging information to reconstruct her travel history and identify the possible source of infection.

WHO representative to Nigeria Pavel Ursu said the information received by the agency indicated that the woman had been in Uganda from 16 September and returned to Abuja on 3 October.

The WHO official said the information available to the agency did not establish that she had travelled outside Uganda.

Patrick Otim, a WHO emergency response manager, also said the source of the infection remained unknown as investigators worked to establish the patient’s movements before she became ill.

One area of investigation is the health facilities the woman visited in Abuja after developing symptoms and before she was hospitalised, including the possibility of exposure to other people during that period, he said.

Meanwhile, the Ugandan government said that the country had no active Ebola cases.

Uganda recorded 20 Ebola cases between May and June, most of them linked to infections imported from the DRC. The WHO declared the country’s outbreak over in August after 42 days without a new confirmed case.

Nigeria’s response

The uncertainty surrounding the woman’s travel history comes as Nigeria works to prevent further transmission following confirmation of the imported infection on 20 October.

As PREMIUM TIMES reported, the patient is a 42-year-old woman who lives in Abuja and recently travelled to Uganda. She developed symptoms on 6 October, three days after returning to Nigeria, and initially sought treatment at a private hospital, believing she had malaria.

She later visited another private hospital, where she was admitted on 11 October after her condition failed to improve. Her infection was subsequently confirmed through laboratory testing.

PREMIUM TIMES also reported that health authorities had identified 44 people who might have been exposed to the patient, including healthcare workers, patients, caregivers and travel contacts.

The government has begun contact tracing and is working with international partners to establish the woman’s movements and identify anyone who may have been exposed.

The WHO has urged Nigerians to remain calm, explaining that one confirmed imported case does not, by itself, mean the country is experiencing an Ebola ‘outbreak’. The agency is supporting Nigeria with case investigation, laboratory testing, contact tracing and infection prevention measures.

Regional outbreak

Nigeria’s case comes amid an Ebola outbreak that was declared in the DRC in May and has spread to other African countries, raising concerns about cross-border transmission.

The outbreak is caused by the Bundibugyo virus, a species of Ebola virus for which there is currently no licensed vaccine.

Kenya has also reported cases linked to the movement of the virus across borders, adding to concerns about the challenges of tracing infections among international travellers.

Ebola spreads through direct contact with the blood or other bodily fluids of an infected person, or with contaminated materials. Symptoms may include fever, headache, weakness, vomiting and diarrhoea.


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